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Metroid: Zero Mission has 3 difficulty levels, and on Hard mode missile expansions only grant you 2 missiles. Doors have no memory of how many missiles they've been hit by if you leave that room and come back, meaning that until you've picked up 2 additional missile expansions, every missile door will require you to rely on RNG drops from enemies for refills inside that room.

You could fire 2 missiles into the door, then kill a dozen enemies in the room and not get any more missiles, or only get enough missiles to shoot the first red door 2 more times, then you have to leave the room to restock and try again, potentially repeating this whole process multiple times, grinding the fast pace of Zero Mission to a tedious halt when you've only just begun the game.

This is bad enough by itself, but if you're doing a low percentage run on Hard, this will continue to be an issue throughout the entire run, potentially even making some doors impossible to open if there are no enemies in that room which can drop missile refills (I say potentially because I can't remember if there are rooms like that).

I'm not sure if it would be possible to give doors a separate number of missiles to require for separate difficulties (let's say 2 missiles for Hard), but if that was possible and was implemented, then I'd have no complaints. Similarly, Easy could have its missile requirements reduced from 5 as well, to make it easier - anything above 1 missile would still be more than it requires without this hack.

It makes the game more similar to 1986 Metroid and gives missile upgrades more meaning. Very happy!